Pericytes Potential to Reverse Heart Damage

Pericytes Potential to Reverse Heart Damage

New pericytes discovery could reverse tissue damage caused by heart attacks A new discovery by University of Bristol scientists helps to explain how cells which surround blood vessels, called pericytes, stimulate new blood vessels to grow with the hormone ‘leptin’ playing a key role. Leptin is produced by fat cells which helps to regulate energy […]

microneedle patches with influenza vaccine

Microneedle Patches for Flu Immunisation Phase I Trial

Microneedle patches provide an alternative to conventional needle-and-syringe immunisation, and potentially offer improved immunogenicity, simplicity, cost-effectiveness, acceptability, and safety. In a recent Phase I trial, safety, immunogenicity, and acceptability of the first-in-man study on single, dissolvable microneedle patch vaccination against influenza was evaluated. The influenza vaccine can offer the best available protection against the flu […]

Canakinumab Drug Phase III Study Reducing Heart Attacks

Canakinumab Drug Phase III Study Reducing Heart Attacks

Novartis Phase III study shows ACZ885 (canakinumab) reduces cardiovascular risk in people who survived a heart attack Phase III CANTOS study met the primary endpoint, a composite of heart attack, stroke and cardiovascular death, showing that ACZ885 (canakinumab) in combination with standard of care therapy reduces cardiovascular risk in people with a prior heart attack […]

Beetroot Juice May Provide Benefits to Heart Disease Patients

Beetroot Juice May Provide Benefits to Heart Disease Patients

Nitrate supplementation [Beetroot Juice] decreases sympathetic nerve responses that contribute to heart disease risk Bethesda, Md. (May 10, 2017)—A new study finds that dietary nitrate—a compound that dilates blood vessels to decrease blood pressure—may reduce overstimulation of the sympathetic nervous system that occurs with heart disease. The research team looked specifically at beetroot juice, a […]

Favourable Effects of Vitamin D in Chronic Heart Failure - VINDICATE Study Dr Klaus Witte

Favourable Effects of Vitamin D in Chronic Heart Failure – VINDICATE

Favourable effects of vitamin D on cardiac function in patients with chronic heart failure secondary to left ventricular systolic dysfunction – the results of the MRC-funded VINDICATE Study A daily dose of vitamin D3 improves heart function in people with chronic heart failure, a five-year University of Leeds research project has found. Dr Klaus Witte, […]

Early Success with HVAD LATERAL trial Medtronic

Early Success with HVAD LATERAL Trial

Clinical Trial of Medtronic Heart Pump HVAD Delivers Positive Results with Less-Invasive Implant Procedure   Medtronic plc announce results of the ENDURANCE Supplemental trial in a late-breaking clinical trial session of the 2017 International Society for Heart and Lung Transplantation (ISHLT) Scientific Meeting in San Diego. The study evaluated the company’s HVAD(TM) System as a […]

Social Network Support for Heart Failure? – NIHR CLAHRC Wessex Research

Social Network Support for Heart Failure? – NIHR Research

NIHR CLAHRC Wessex – How Social Network Community Support Aids Management of Long-Term Conditions – Can You Help? Our friends at the National Institute for Health Research CLAHRC Wessex are calling for people with Heart Failure and other long term conditions to help inform them of the help they receive from social network and online support groups to […]